In a recent study by Cheng et al. [158], collagen type V alpha 2 chain (COL5A2) and lipoprotein lipase (LPL) were found to be significantly higher in ovarian cancer cell line-derived EVs than in ovarian surface epithelial cells (HOSEPiC) (p < 0.05). This evidence concerns the gene COL5A2 and ovarian carcinoma.