Last but not least, P-JNK and P-Tau (Ser202, Thr205) colocalize at mitochondrial sites with the non-fibrillar neurotoxic form of alpha-synuclein (Pα-syn), which is a truncated and phosphorylated synuclein found in Parkinson disease, that triggers mitochondrial damage [104]. Here, SNCA is linked to Parkinson disease.