Intravenous GLP-1 administration at a pharmacological dose (0.9 pmol/kg/min) attenuates the fall in SBP and DBP (~5 mmHg at 60 min) in response to a carbohydrate meal in T2D (Figure 2) and does so variably in “healthy” older individuals [3,7]. This evidence concerns the gene GLP1R and type 2 diabetes mellitus.