Indeed, non-IgE-mediated FAs include food protein-induced allergic proctocolitis (FPIAP), food protein-induced enterocolitis syndrome (FPIES) eosinophilic disorders, including eosinophilic esophagitis (EoE), and a heterogeneous group of non-IgE-mediated disorders more commonly recognized as gastrointestinal motility disorders [6,7]. The gene discussed is IGHE; the disease is eosinophil disorder.