Interestingly, gut disbiosis was found in TLR7-dependent murine models of SLE, and bacterial translocation of Lactobacillus reuteri into the liver and the secondary lymph organs can drive autoimmunity, which was prevented by dietary resistant starch by suppressing the abundance and translocation of L. reuteri through short-chain fatty acids (SCFAs) [22]. Here, TLR7 is linked to systemic lupus erythematosus.