SG leads to important improvements in aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglycerides and high-density lipoprotein (HDL) serum levels [112,113], complete NAFLD resolution assessed with ultrasound imaging (especially in those who achieved more than 50% excess weight loss [114]) and histological amelioration [115]. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.