The apparent obesity-related increase in the oxidation of 0.1 mmol/L Bza by adipose depots was confirmed by enzyme kinetics of AOC3 activity, since the Vmax for the oxidation of increasing doses of benzylamine was, when expressed as pmoles of produced H2O2/mg protein/min, 212 ± 22 for SCWAT from db+/- and 440 + 72 for SCWAT from db-/- mice (n = 7, p < 0.05). The gene discussed is AOC3; the disease is Obesity.