With regard to individual studies of cranberry juice, supplementation significantly increased HDL-C in adults with abdominal obesity [13], reduced triglycerides in healthy adults [14], and reduced apolipoprotein B and increased apolipoprotein A-I in patients with type 2 diabetes [15] but had no effect in other studies [16,17,18,19]. The gene discussed is APOB; the disease is Abdominal obesity.