More data on manganese status among IBD patients could be useful, considering that currently, manganese is a less studied trace element for this patient category, although it has an important antioxidant role, as part of manganese-superoxide dismutase and also as a cofactor of xantinoxidase, arginase, pyruvate decarboxylase and glutaminsynthetase [43]. The gene discussed is GLUL; the disease is inflammatory bowel disease.