Inflammatory markers (CRP, TNF-α, IL-1β, IL-6), body composition (assessed by Dual Energy X-Ray Absorptiometry-DXA-and vector impedance analysis), empty sensation (assessed by visual-analogic scale and peptide YY), pro/antioxidant ratio (assessed by trimethylamine N-oxide, TMAO), hormonal (assessed by ghrelin, leptin, adiponectin and glucagon like peptide 1, GLP-1) and lipo-metabolic profile, such as cholesterol profile, triglycerides (TG), and glycemic profile, were determined in adults affected by obesity. This evidence concerns the gene GCG and obesity disorder.