TP53 and colonic neoplasm: In the non-tumor colon cancer cell line CCD-18Co, the GI50 value was approximately 2-fold higher than that obtained in the HCT116 p53+/+ (16.5 ± 2.2 μM, n = 4 independent experiments), which revealed some selectivity of TrxFTL for the tumor cells of the colonic tissue.