A significant difference in the expression of IL-6 by B cells was observed after stimulation with HERV-K env 109–126 peptide in ALS patients compared to HCs with statistically significant p value (ALS vs. HCs mean ± SD = 0.641 ± 0.31 vs. 0.234 ± 0.14; p = 0.0127) (Figure 3a). Here, IL6 is linked to amyotrophic lateral sclerosis.