In another study, we demonstrated that promoting ABCA1-mediated cholesterol efflux similarly prevents renal disease progression in an experimental model of FSGS (adriamycin-induced nephropathy) and of Alport syndrome (Col4a3 KO mice) in association with reduced formation of lipid droplets in glomeruli and reduced accumulation of cholesterol esters in kidney cortices. This evidence concerns the gene ABCA1 and focal segmental glomerulosclerosis.