According to Shou-Qing Li et al., PAK4 could be a possible target of miR-199a/b-3p with an oncosuppresive role: in human breast cell lines, ectopic expression of miR-199a/b-3p blocks the PAK4/MEK/ERK pathway to inhibit breast cancer progression by inducing G1 phase arrest [52]. The gene discussed is MAP2K7; the disease is breast carcinoma.