When adjusting by all potential confounders in the repeated-measures generalized model, including age, sex, smoking history, diabetes mellitus, hypertension, coronary artery disease, cerebrovascular disease, duration of HD, albumin, total cholesterol, triglyceride, fasting glucose, HbA1c, uric acid, calcium–phosphorous product, Kt/V, ultrafiltration rate, and medications use, using the estimated slopes by a repeated-measures generalized model showed 0.24 (95% CI, 0.13 to 0.35; p < 0.0001) for CTR and 0.08 (95% CI, 0.002 to 0.16; p = 0.0441) for AoAC. This evidence concerns the gene ALB and Hypertension.