Although the mRNA expression of CaMKII’s endogenous inhibitor CAMK2N1 inversely correlates with the severity of medullary thyroid carcinoma [53], both CAMK2N1 (HR=2.1) and CAMK2A (HR=1.6) were overexpressed in the TCGA HNSCC patientswith worse outcomes. The gene discussed is CAMK2N1; the disease is head and neck squamous cell carcinoma.