NUDT15 and acute lymphoblastic leukemia: In 100 Thai children with ALL, those with mono- or bi-allelic variants of NUDT15 c.415C>T and c.55_56insGAGTCG showed lower neutrophil counts compared with those with wild-type variants, although the adjusted doses during the first 6 months of maintenance therapy for NUDT15 wild-type, mono-allelic, and bi-allelic variants were 50.0, 36.6, and 12.5 mg/m2/day, respectively [29].