We compared the performance of the two GBM models for predicting survival rates (Model 1: T stage, N stage, histological grade, lymphatic invasion, ER status, and HER2 status versus Model 2: BMI1 expression level, T stage, N stage, histological grade, lymphatic invasion, ER status, and HER2 status). The gene discussed is ESR1; the disease is glioblastoma.