After adjustment for variables including waist circumference, SBP, DM duration, HbA1c, albuminuria categories, lipid profiles, and for DM medications, patients with FTO (rs8050136) polymorphism were significantly associated with increased DR risk (OR, 5.851; CI, 1.201–28.510; FDR-corrected p = 0.039), whereas those with PSMD6 (rs831571) polymorphisms were not (p = 0.076) (Table 4). The gene discussed is FTO; the disease is diabetes mellitus.