SOAT1 and infection: Infections are detected via pattern recognition receptors (PRRs) [11,12,13], which activate pathogen-specific signaling pathways [9,13,14]: the Toll pathway (for Gram-positive bacteria and fungi), the Immune deficiency (IMD) pathway (Gram-negative), with some exceptions in both cases, and the Janus Kinase and Signal Transducer and Activator of Transcription (JAK/STAT) pathway [15].