To analyze the effect of stress levels on total RQLQ score, the multiple regression model was adjusted for institute, age, sex, income, education, smoking status, high-risk drinking, number of siblings, BMI, asthma, hypertension, diabetes, number of colds per year, global VAS score, VAS score for ocular discomfort, VAS score for epiphora, AR severity based on ARIA classification, eosinophil count, total IgE, and number of positive allergen groups on the SPT (Table 3). This evidence concerns the gene IGHE and hypertensive disorder.