Based on the beneficial therapeutic profile of SGLT2 inhibitors and the experience of their use in non-hospitalised patients, we aimed to retrospectively analyse the glycaemic and clinical efficacy and safety of empagliflozin continuation in combination with basal insulin compared to a basal-bolus insulin regimen in patients with T2D hospitalised for acute decompensated HF. The gene discussed is SLC5A2; the disease is hydrops fetalis.