We found that an in-hospital antihyperglycaemic regimen that includes the continuation of empagliflozin achieved effective glycaemic control and was associated with greater cumulative urine output and lower NT-proBNP levels than a conventional basal-bolus insulin regimen in patients with T2D hospitalised for acute decompensated HF. The gene discussed is INS; the disease is type 2 diabetes mellitus.