Moreover, as shown by our study, girls with PCOS, despite their young age, differed significantly from the control group in terms of metabolic indicators, such as waist circumference (p < 0.000001), serum LDL-C (p = 0.01), fasting insulin (p = 0.002) and the HOMA-IR index (p = 0.006), which assesses insulin resistance based on the relationship between insulin and blood glucose levels. Here, INS is linked to polycystic ovary syndrome.