BCHE and early-onset autosomal dominant Alzheimer disease: It has been previously reported that chrysin exhibited antioxidant activities by quenching 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals [30], and inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), the enzymes involved in Alzheimer’s disease (AD) pathogenesis and cognitive decline [31].