These include C-reactive protein (CRP), interleukins (IL)-1, -6, and -8, IL-1 receptor antagonist (IL-1Ra), soluble IL-6 receptor (sIL-6R), tumor necrosis factor-alpha (TNF-α), a chemokine promoting macrophage migration, chemokine C-C motif ligand 3 (CCL3), and melanoma inhibitory activity (MIA) [38,39,40,41,42,43]. This evidence concerns the gene TNF and melanoma.