We suggest that some morphological and immunophenotypical features, including diverse architectural patterns, compactly aggregated small tubules, glands containing intraluminal hyaline-like eosinophilic secretions, and variable degrees of PAX2 and GATA3 staining may be designated as MLD in association with common histological subtypes of endometrial carcinoma. The gene discussed is PAX2; the disease is endometrial carcinoma.