TLR2 and TLR4 polymorphisms were associated with various conditions such as asthma [40], pulmonary tuberculosis [32,41], Helicobacter pylori infection [42], as well as alterations in levels of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglycerides [36]. The gene discussed is TLR4; the disease is asthma.