In the CRC patients: (1) with an increase of PLT by 10 × 103/μL, the mean concentration of sCD40L increases 1.024 times (increases by 2.4%); (2) with an MPC increase of 1 g/dL, the average concentration of sCD40L increases 1.14 times (increases by 14%), if other model parameters are fixed (Table 4). This evidence concerns the gene CD40LG and colorectal carcinoma.