REN and congenital adrenal hyperplasia: If there is a strong suspicion of congenital adrenal hyperplasia, therapy can be initiated, not before preserving blood and urine for further serum analysis of other steroids (testosterone, DHT, androstenedione, plasma renin activity, deoxycorticosterone, DHEAs, and others) and urinary/24-h evaluation of urinary steroid profile, which can give clues for the diagnosis of different adrenal enzymatic blocks [43].