CD79A and common variable immunodeficiency: In fact, CVID represents a heterogeneous group of diseases with common clinical and laboratory findings, including hypogammaglobulinemia (IgG in all, IgA in 70–80% and IgM in approximately 50% of affected patients), weak or absent responses against polysaccharide (mainly) and protein antigens and usually very low isotype-switched memory B cell counts in the periphery [2,3].