Alternatively, when considering the overall diagnosis of each patient group, the amount of total Sclerostin was similar in periodontitis, gingivitis and healthy sites of patients with periodontitis (p = 0.10) (Figure 1B), and it was also similar in gingivitis and healthy sites of patients diagnosed strictly with gingivitis (p = 0.30) (Figure 1C). The gene discussed is SOST; the disease is gingivitis.