AFP and neoplasm: It is important to perform HCC surveillance using imaging modalities, such as abdominal ultrasonography, computed tomography, or magnetic resonance imaging, every 6 months, combined with the use of tumor markers such as alpha-fetoprotein, lens culinaris agglutinin-reactive alpha-fetoprotein isoform (AFP-L3), and/or des-γ-carboxy prothrombin (DCP) [11].