During pulp inflammation, the function of miR-223 is still not clear, because, in the study by Huang et al., it was observed that its overexpression in human dental pulp stem cells (DPSCs) significantly increased the levels of dentine sialophosphoprotein (DSPP) and dentine matrix protein (DMP)-1, suggesting that miR-223-3p may be involved in the regulation of odontoblast differentiation during the process of pulpitis repair [88]. This evidence concerns the gene DSPP and pulpitis.