Moreover, it took intensive research work over the past 50 years to identify EPO as the major driver of BM erythropoiesis, purify it from urine derived from patients with aplastic anemia by Goldweisser’s group, clone the EPO gene and produce recombinant EPO, as mentioned earlier [7,8,10,11,12,13]. This evidence concerns the gene EPO and idiopathic aplastic anemia.