More recently, a study investigated the N-glycosylation profile of membrane and secreted proteins in WM266-4 metastatic melanoma cells, providing evidence that GnT-III upregulation does not lead to a total abrogation of the formation of highly branched glycans but modifies these glycans by the introduction of a bisecting N-acetylglucosamine (GlcNAc), modulating their capacity to interact with carbohydrate-binding proteins such as plant lectins [83]. Here, MGAT3 is linked to melanoma.