PICALM and cancer: Most of these proteins have been recently recognized for their role in carcinogenesis and targeted cancer therapy, including, e.g., EIF4A2 [45], ALDH6A1 [46], SEC14L1 [47], METTL17 [48], KDM3A [49], PPT1 [50], SGSH [51], AK4 [52], and PICALM [53].