We next analyzed the ECM composition reflected by collagen signatures in transcriptome datasets from microdissected tubulointerstitial compartments in 170 CKD patients and 31 healthy living donors (Nephroseq database) for an association with established markers of tubular atrophy, including cytokeratin-7 (encoded by KRT7), -18 (KRT18), and -19 (KRT19) [25,37]. The gene discussed is KRT19; the disease is chronic kidney disease.