PODN and neoplasm: Finally, regarding the non-canonical class V SLRPs, PODN transcription levels in healthy tissues of the left colon were greater than those observed in the right (p < 0.05, Mann–Whitney U test), but in tumor samples there was a statistically significant subexpression of around 70% compared to healthy tissue samples from the same patients (p < 0.01, Wilcoxon test, Figure 3A).