Some studies also showed that patients with severe COVID-19 exhibit higher levels of various proinflammatory cytokines, such as IL-2, IL-6, IL-7, IL-10, inducible protein 10, monocyte chemoattractant protein 1, TNF-α, macrophage inflammatory protein 1 alpha, and granulocyte-colony-stimulating factor [108,110,111]. This evidence concerns the gene TNF and COVID-19.