TP53 and schistosomiasis: Significant amounts of N7-guanine-AFB1 adducts and novel adenine adducts (p < 0.01) were detected in patients with schistosomiasis, mostly in patients infected with S. haematobium or a combination of both species, suggesting that schistosomiasis and exposure to aflatoxin B1 act synergistically to increase the incidence of p53 gene mutations [129].