COL3A1 and idiopathic pulmonary fibrosis: First shown in 2012, of >14,000 genes represented by on the Illumina HumanMethylation27 BeadChip, 870 genes were differentially methylated in IPF lung tissue compared to controls, 35 of which linked to differential expression of the annotated gene [54] including previously identified IPF associated genes including MMP7 and COL3A1.