CD8A and colorectal carcinoma: As expected, MYC/CXCL8/TIMP1 gene expression levels displayed associations with tumor purity and were positively correlated with infiltrating levels of CD8+ T cells and macrophages (p < 0.05), and were correlated with the abundances of tumor infiltrates including CD8+ T cells, macrophages and DCs in CRC (Figure 6).