Considering that epigenetic factors play a role in the control of FTMT expression and that the conditions to upregulate the expression of FtMt are milder [25] than those used to increase the expression of frataxin mRNA in the FRDA model [61], a therapeutic application of FtMt to prevent and reduce the effects of Friedreich ataxia has been proposed. The gene discussed is FXN; the disease is Friedreich ataxia.