CCR5 and Granuloma: The associations found between polymorphisms in CCR5, CCR2 [34], and sarcoidosis, including the present study, and the expression of the chemokines in the sarcoidosis granuloma suggest that genetic variants that cause decreased or dysfunctional chemokine receptors could lead to the formation of less stable granuloma, which in turn could lead to less prolonged disease, such as the Löfgren’s syndrome phenotype of sarcoidosis.