In the context of differentially expressed (DE)-genes related to asthenozoospermia, special attention has recently been focused on Cysteine-Rich Secretory Protein 2 (CRISP2), Cation Channel Sperm Associated 1 (CATSPER1) and Prostate and Testis Expressed 1 (PATE1) [19,20,21,22,23]. Here, CRISP2 is linked to Reduced sperm motility.