It is noteworthy that several other genes that were upregulated by αvβ3 integrin signaling are associated with various types of glaucoma and IOP regulation (Table 2, Table 3 and Table 4) further supporting the idea that αvβ3 integrin and the concomitant increase in TGFB2 expression together may be playing a role in glaucoma. Here, TGFB2 is linked to glaucoma.