In another study, using transgenic mice expressing a constitutively active form of Ikkβ in muscle stem cells, a link between stem cell functional exhaustion and NF-κB-dependent telomere shortening was established in disease-related chronic injuries such as in Duchenne muscular dystrophy [173], suggesting that maintaining telomere length of muscle stem cells could improve its regenerative capacity also in normal and pathological ageing, not only in DMD. The gene discussed is IKBKB; the disease is Duchenne muscular dystrophy.