TNF and COVID-19: Furthermore, neutrophils were the main cells found in bronchoalveolar lavage fluid (BALF) and in peripheral blood, associated with high levels of D-dimer, ferritin, and inflammatory cytokines (such as tumor necrosis factor-TNF and IL-6), suggesting the participation of these cells in coagulopathy, systemic inflammation, and severe acute respiratory syndrome associated with COVID-19 [104].