PDGFRB and neoplasm: Among other markers upregulated in PAX7+ cells were: CD97, a widely expressed adhesion class G-protein-coupled receptor (aGPCR) that was previously found to be upregulated in RMS compared to skeletal muscles [36]; CD140B, known as PDGFRB important in RMS progression [37]; insulin receptor CD220 and insulin-like growth factor-1 receptor CD221, both associated with worse RMS survival [38] and activated leukocyte cell adhesion molecule (ALCAM), and CD166 associated with tumor invasiveness [39].