NFKB1 and extranodal nasal NK/T cell lymphoma: Low miR-146a expression was demonstrated to be an independent poor prognostic factor in NKTCL, while in NKTCL cell-lines, miR-146a overexpression inhibited NFκB activity, suppressed cell proliferation, induced apoptosis, and enhanced chemosensitivity, suggesting it functions as a tumor suppressor [115].